Artikel
Workshop "Mass spectrometry in zoonoses research" 2012
Glycolipids as key molecules Since a large number of viral and bacterial zoonotic agents and the virulence factors (toxins) they produce bind to glycoconjugates on the cell surface of their target cells, this course focused on glycolipids as potential receptor molecules. These consist of a double-tailed lipid anchor, the so-called ceramide (sphingosine plus fatty acid), and an oligosaccharide part, which is characterized by a high variability due to the different number and linkage type of sugars. Glycolipids are found in the outer layer of the plasma membrane of human and animal cells